HIGHLIGHTS
- who: Paul Erlich from the (UNIVERSITY) have published the research work: Complement Protein C1q Forms a Complex with Cytotoxic Prion Protein Oligomers, in the Journal: (JOURNAL) of June/18,/2010
- what: In the present work, the use of a specific C1 activation assay requiring lower protein concentrations allowed the authors to demonstrate that the smaller type II oligomers, comprising 8 -15 PrP molecules, are the most efficient activators of complement, compared with larger oligomers (types I and I⬘).
SUMMARY
NUMBER 25 JOURNAL OF BIOLOGICAL CHEMISTRY Recombinant ovine PrP has been shown . . .
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