Complete response to talazoparib in patient with pancreatic adenocarcinoma harboring somatic palb2 mutation: a case report and literature review

HIGHLIGHTS

  • who: Andrei Kachmazov from the National Cheng Kung University Hospital, Taiwan have published the research work: Complete response to talazoparib in patient with pancreatic adenocarcinoma harboring somatic PALB2 mutation: A case report and literature review, in the Journal: (JOURNAL)
  • what: This clinical case highlights the importance of NGS testing for PDAC patients.

SUMMARY

    Chemotherapy regimens continue to dominate the treatment paradigm for PDAC patients despite the distinctive chemo-resistance of this disease. After a longtime struggle to find targets of interest and novel drugs beyond chemotherapy the poly(adenosine_diphosphate-ribose) polymerase . . .

     

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