HIGHLIGHTS
- who: Cardiomyopathy et al. from the Department of Medicine, University of Cambridge, Cambridge, United Kingdom, MRC Mitochondrial Biology Unit, Cambridge, United Kingdom, Wolfson Brain have published the research work: Complex I Deficiency Due to Selective Loss of Ndufs4 in the Mouse Heart Results in Severe Hypertrophic Cardiomyopathy, in the Journal: PLOS ONE | www.plosone.org of November/27,/2013
- what: The authors demonstrate that selective disruption of the Ndufs4 gene in the heart leads to a,50% decrease in complex I activity, that in turn drives severe hypertrophic cardiomyopathy, as determined by magnetic_resonance imaging (MRI . . .
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