HIGHLIGHTS
- who: Raphau00ebl Dos Reis from the CNRS thu00e9rapeutiques, Paris, FranceUniversity of have published the paper: Complex regulation of Gephyrin splicing is a determinant of inhibitory postsynaptic diversity, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
- what: The authors show that inhibitory synapses harbor distinct combinations of GPHN protein isoforms, either at synapses present at specific subcellular locations or containing distinct GABA-A receptors. This approach provides high throughput long-read sequencing of full-length transcripts, and therefore the complete analysis of exon combinations incorporated in distinct splice variants. The authors characterize the profiles of GPHN epitopes . . .
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