Composite biomarkers derived from micro-electrode array measurements and computer simulations improve the classification of drug-induced channel block

HIGHLIGHTS

  • who: Jean-Frédéric Gerbeau from the University of Zaragoza, Spain have published the paper: Composite Biomarkers Derived from Micro-Electrode Array Measurements and Computer Simulations Improve the Classification of Drug-Induced Channel Block, in the Journal: (JOURNAL)
  • what: One of the main goals of safety pharmacology studies is to anticipate how drugs affect cardiomyocytes. The authors propose a way to automatically extract features from the MEA measurements that are designed to perform well in a classification context. To predict the effects of drugs onto channel block, the authors propose to adopt a Machine . . .

     

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