Compositionally aware phylogenetic beta-diversity measures better resolve microbiomes associated with phenotype

HIGHLIGHTS

  • who: Cameron Martino and colleagues from the University of California Department of Pediatrics, University of California School of Medicine, La Jolla, California, USA have published the paper: Compositionally Aware Phylogenetic Beta-Diversity Measures Better Resolve Microbiomes Associated with Phenotype, in the Journal: (JOURNAL)
  • what: The authors show using simulated and real data that the new methods provide improved classification accuracy of ordinal sample clusters and increased effect size between sample groups on beta-diversity distances. The authors propose an extension to RPCA and CTF, called phylogenetic-RPCA and -CTF (phylo-RPCA -CTF), that accounts for . . .

     

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