Comprehensive analysis of transcriptomic profiles identified the prediction of prognosis and drug sensitivity of aminopeptidase- like 1 (npepl1) for clear cell renal cell carcinoma

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SUMMARY

    Renal cell carcinoma (RCC) is one of the most common malignancies among urological carcinomas, representing 80% of renal malignancies. Exogenous amino_acids are essential for the survival of tumor cells. Te stable state of amino_acids and proteins essential for cells depends on the catalytic cleavage of amino_acids at the amino terminus of proteins by aminopeptidases. Kaplan-Meier curves were applied to predict the prognosis of ccRCC patients between low and high NPEPL1 expression groups and indicated that the high NPEPL1 expression group had a poor prognosis. Te importance of some infltrating immune cells has been . . .

     

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