Comprehensive interpretation of in vitro micronucleus test results for 292 chemicals: from hazard identification to risk assessment application

HIGHLIGHTS

  • who: Byron Kuo from the (UNIVERSITY) have published the Article: Comprehensive interpretation of in vitro micronucleus test results for 292 chemicals: from hazard identification to risk assessment application, in the Journal: (JOURNAL) of October/22,/2020
  • what: In this study MNvit datasets for 292 chemicals generated by the the authors EPA's ToxCast program were evaluated using a decision tree-based pipeline for hazard identification. Using the approach described in Bryce et_al (Environ Mol Mutagen 52:280-286 2011) the authors identified 15 (5%) aneugens. Using this approach, one plate was identified as an outlier . . .

     

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