Comprehensive proteomic analysis of autophagosomes derived from leishmania-infected macrophages

HIGHLIGHTS

  • who: Devki Nandan and colleagues from the Division of Infectious Diseases, Department of Medicine, University of British Columbia, Vancouver, British Vancouver, British Columbia, Canada have published the Article: Comprehensive proteomic analysis of autophagosomes derived from Leishmania-infected macrophages, in the Journal: PLOS ONE of October/26,/2022
  • what: The authors showed that L donovani modulates the composition of macrophage autophagosomes during infection when compared to autophagosomes induced by either rapamycin (selective autophagy) or starvation (non-selective autophagy).
  • how: The authors used stable isotope labeling by amino acid in cell culture and liquid chromatography . . .

     

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