Comprehensive screening strategy coupled with structure-guided engineering of -threonine aldolase from pseudomonas putida for enhanced catalytic ef fi ciency towards – threo -4-methylsulfonylphenylserine

HIGHLIGHTS

• who: January et al. from the Zhejiang University Technology, China have published the Article: Comprehensive screening strategy coupled with structure-guided engineering of -threonine aldolase from Pseudomonas putida for enhanced catalytic ef fi ciency towards - threo -4-methylsulfonylphenylserine, in the Journal: (JOURNAL)
• what: This study provides a promising method for addressing the challenge of engineering TA enzymes to efficiently prepare u03b2-hydroxy-u03b1-amino_acids with two chiral sites by monitoring the aldol condensation activity.
• how: The results showed that only NaOH produced the clear red-brown color . The DS algorithm results indicated that . . .
  

   

  

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