Computational analysis and experimental testing of the molecular mode of action of gatastatin and its derivatives

HIGHLIGHTS

  • who: Paola Vottero and collaborators from the Department of Biomedical Engineering, University of Alberta, Edmonton, AB T G , Canada have published the Article: Computational Analysis and Experimental Testing of the Molecular Mode of Action of Gatastatin and Its Derivatives, in the Journal: Cancers 2023, 15, 1714. of /2023/
  • what: This work aims to identify the binding sites and modes of and derivatives through molecular-docking simulations. To this, studies by Katsetos et_al showed that both TUBG1 and TUBG2 were overexpressed in glioblastoma ; therefore, the analysis of the binding_sites focused entirely on tubulin u03b3I.
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