HIGHLIGHTS
- who: Vardges Tserunyan from the (UNIVERSITY) have published the research work: Computational analysis of 4-1BB-induced NFu03baB signaling suggests improvements to CAR cell design, in the Journal: (JOURNAL)
- what: Particularly the authors propose specific manipulations to the NFu03baB signal transduction pathway that can fine-tune the response of CD19scFv-41BB cells to the antigen concentrations they are likely to encounter. This work has shown that the pathway can encode approximately 1 bit of information at most, i.e., whether the extracellular stimulus is present or absent . Altogether, the authors provide a quantitative framework that . . .
If you want to have access to all the content you need to log in!
Thanks :)
If you don't have an account, you can create one here.