Computational approaches for rna structure ensemble deconvolution from structure probing data

HIGHLIGHTS

  • who: Sharon Aviran from the University of Groningen , Biomedical Engineering Department and Genome Center, University of California, Davis, CA, USA have published the article: Computational Approaches for RNA Structure Ensemble Deconvolution from Structure Probing Data, in the Journal: (JOURNAL)
  • what: The aim of the normalization is to enable the direct comparison of RNA reactivity profiles across different experimental conditions. Differences include the stage in the analysis at which the data are considered, their integration with thermodynamics, modeling assumptions, model fitting techniques, and the output ensemble description. In terms of sequence lengths to which this approach . . .

     

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