Concepts in immuno-oncology: tackling b cell malignancies with cd19-directed bispecific t cell engager therapies

HIGHLIGHTS

  • who: Andreas Viardot from the Department of Internal Medicine III, University Hospital Ulm, Ulm, Germany have published the research: Concepts in immuno-oncology: tackling B cell malignancies with CD19-directed bispecific T cell engager therapies, in the Journal: (JOURNAL)
  • what: The CD19 BiTE therapy blinatumomab has validated the BiTE immuno-oncology platform and raised B-ALL treatment standards, with the first approval of any drug to treat MRD.
  • future: Some limitations need to be addressed additional investigation is needed to understand the impact of stepwise dosing on the efficacy of blinatumomab treatment for . . .

     

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