Concepts of pathogenesis in psoriatic arthritis: genotype determines clinical phenotype

HIGHLIGHTS

  • who: Oliver FitzGerald and collaborators from the involving diverse immunoreactant molecules and mediators such as cytokines may be unleashed that help to determine clinical disease expressionAs mentioned, this is a testable hypothesis with RNA genome sequencing and protein and cytokine profiling of very wellcharacterised clinical phenotypic/genotypic groupings likely to reveal consistent differences between the genotypic groupings. Abbreviations HLA: human leukocyte antigen have published the Article: Concepts of pathogenesis in psoriatic arthritis: genotype determines clinical phenotype, in the Journal: (JOURNAL)
  • what: The authors show that these two cohorts differ considerably in their predominant HLA alleles . . .

     

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