Concurrent inhibition of akt and erk using tic-10 can overcome venetoclax resistance in mantle cell lymphoma

HIGHLIGHTS

• who: Agnete Marie Granau et al. from the Biotech Research and Innovation Centre (BRIC), University of Copenhagen, Copenhagen, Denmark have published the research work: Concurrent Inhibition of Akt and ERK Using TIC-10 Can Overcome Venetoclax Resistance in Mantle Cell Lymphoma, in the Journal: Cancers 2023, 15, 510. of 13/01/2023
• what: The authors aimed to investigate the molecular mechanisms of acquired venetoclax resistance (VR) in MCL cell lines, as well as the effects of the microenvironment in generating a VR phenotype in MCL.
• how: For co-cultures of MCL cells and . . .
  

   

  

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