Concurrent outcomes from multiple approaches of epistasis analysis for human body mass index associated loci provide insights into obesity biology

HIGHLIGHTS

  • who: Sheldon Du2019Silva from the Centre have published the Article: Concurrent outcomes from multiple approaches of epistasis analysis for human body mass index associated loci provide insights into obesity biology, in the Journal: Scientific Reports Scientific Reports
  • what: The analysis shows that variants at genomic loci in or near FTO and MC4R; RHBDD1 and MAPK1, exhibit reproducible pairwise interactions associated with human BMI. This analysis shows the importance of deciphering the simultaneous effects from multiple SNPs acting in conjunction to influence the phenotypes of the interest in large-scale population datasets. Similarly, the authors examine . . .

     

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