Conditional ablation of myeloid tnf increases lesion volume after experimental stroke in mice, possibly via altered erk1/2 signaling

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• who: Bettina Hjelm Clausen from the DepartmentUniversity of Hospital, SdrBoulevard, Odense C, Denmark. have published the research work: Conditional ablation of myeloid TNF increases lesion volume after experimental stroke in mice, possibly via altered ERK1/2 signaling, in the Journal: Scientific Reports Scientific Reports
• what: Using LysMcreTNFfl/fl conditional KO mice with specific ablation of TNF in myeloid cells, including microglia, the authors demonstrate that microglial-derived TNF contributes to TNF-mediated protective effects in experimental stroke. The study was performed on post mortem brain tissue from two stroke cases obtained from the Department of . . .
  

   

  

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