Conditional deletion of neurexin-2 alters neuronal network activity in hippocampal circuitries and leads to spontaneous seizures

HIGHLIGHTS

  • who: Mulatwa T. Haile from the (UNIVERSITY) have published the paper: Conditional deletion of Neurexin-2 alters neuronal network activity in hippocampal circuitries and leads to spontaneous seizures, in the Journal: (JOURNAL) of 12/Nov/2022
  • how: The mEPSCs results showed that the increased immature spine density may not be functional or does not influence overall synaptic function. The data showed that Nrxn2 cKO might not share the canonical role as other Nrxns.
  • future: Future investigations on the synaptic function and behaviors mediated by the corticostriatal circuits would expand the current understanding of . . .

     

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