Conditional transgenic expression of pim1 kinase in prostate induces inflammation-dependent neoplasia

HIGHLIGHTS

• who: Maja Narlik-Grassow and colleagues from the Centre, Madrid, Spain, Instituto de Biomedicina de Sevilla (IBiS), Hospital Universitario Virgen del Rocio, Consejo Superior de Investigaciones Cientificas, Universidad de have published the paper: Conditional Transgenic Expression of PIM1 Kinase in Prostate Induces Inflammation-Dependent Neoplasia, in the Journal: PLOS ONE | www.plosone.org of October/11,/2012
• what: Similar to other transgenic or KO models in the prostate , the model showed that increased expression of Pim1 alone, or in combination with loss of one Pten allele, was not sufficient to produce adenocarcinoma; however, Pim expression . . .
  

   

  

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