HIGHLIGHTS
- who: Niklas Handin from the of Pharmacy, Uppsala University, Uppsala, Sweden have published the paper: Conditions for maintenance of hepatocyte differentiation and function in 3D cultures, in the Journal: (JOURNAL) of November/19,/2021
- what: The authors focused on ADME proteins relevant for drug metabolism and toxicity in functional studies. During the course of the study , impressive results in predicting drug-induced liver injury were reported for PHH spheroids in the 96-well format (Vorrink et_al, 2018). The authors characterize and identify differences and similarities between cell-culture media used for long-term cultivation of . . .
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