HIGHLIGHTS
- who: Avinash Khadela and colleagues from the Department of Pharmacology, LMCollege of Pharmacy, Navrangpura, Ahmedabad, Gujarat, India Institute for Health and Sport, Victoria University, Melbourne, VIC, Australia have published the paper: Configuring Therapeutic Aspects of Immune Checkpoints in Lung Cancer, in the Journal: Cancers 2023, 15, x FOR PEER REVIEW of 16/01/2023
- what: The major reason for this downregulation is the CD28-mediated inhibition of various signaling pathways, including phosphoinositide3 kinase Ak strain transforming (PI3K/AKT) and Rat sarcoma virus/mitogen-activated protein kinase/extracellular signal-regulated kinase (RAS/MEK/ERK) .
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