Confinement anisotropy drives polar organization of two dna molecules interacting in a nanoscale cavity

HIGHLIGHTS

  • who: Zezhou Liu from the McGill University have published the research: Confinement anisotropy drives polar organization of two DNA molecules interacting in a nanoscale cavity, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
  • what: In this communication the authors develop a drastically simplified model system, containing two dsDNA molecules interacting in an elliptical nanoscale compartment (Fig 1), to serve as a minimal model to explain how polymer-polymer interaction in anisotropic confinement can give rise to states with polar organization. By confining two differentially stained dsDNA molecules of equal size in elliptical compartments of varying eccentricity . . .

     

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