Conformational dynamics and putative substrate extrusion pathways of the n-glycosylated outer membrane factor cmec from campylobacter jejuni

HIGHLIGHTS

  • who: Kahlan E. Newman and Syma Khalid from the School of Chemistry, University of Southampton, Southampton, United Kingdom, Department of have published the research work: Conformational dynamics and putative substrate extrusion pathways of the N-glycosylated outer membrane factor CmeC from Campylobacter jejuni, in the Journal: (JOURNAL) of January/13,/2023
  • what: The authors show that the glycans are more conformationally labile than had previously been thought. The authors investigate the orientation preference of these molecules within the channel, and propose a mechanism of translocation for the anionic CDCA substrate. Recent in silico studies of . . .

     

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