Conformational plasticity of centrin 1 from toxoplasma gondii in binding to the centrosomal protein sfi1

HIGHLIGHTS

  • who: Luca Bombardi and colleagues from the Department of Biotechnology, University of Verona, Strada Le Grazie, Verona, Italy have published the research work: Conformational Plasticity of Centrin 1 from Toxoplasma gondii in Binding to the Centrosomal Protein SFI1, in the Journal: Biomolecules 2022, 1115 of /2022/
  • what: One limitation of this study is that a peptide can freely bind TgCEN1 in conformations that are less constrained compared to the intact protein.
  • how: For all the experiments in this work the authors used a recombinant variant of TgCEN1 that lacks the first 21 N . . .

     

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