HIGHLIGHTS
- who: Marcos Matamoros from the (UNIVERSITY) have published the research work: Conformational plasticity of NaK2K and TREK2 potassium channel selectivity filters, in the Journal: (JOURNAL) of 18/05/2022
- what: Using single molecule FRET (smFRET), the authors show that the SF of NaK2K, but not of non-selective NaK, is iondependent, with the constricted SF configuration stabilized in high K+ conditions. This study provides key evidence that this is indeed a general phenomenon, relevant to the whole K+ channel superfamily.
- future: While more extensive studies will be needed to fully understand the partial . . .
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