Conformational rearrangements regulating the dna repair protein ape1

HIGHLIGHTS

• who: Nina Komaniecka et al. from the Biofisika Institute (UPV/EHU, CSIC), University of the Basque Country (UPV/EHU), Leioa, Spain have published the Article: Conformational Rearrangements Regulating the DNA Repair Protein APE1, in the Journal: (JOURNAL)
• what: The authors aim to explore the spatial configuration of the N-terminal region of APE1 when bound to abasic DNA or to NPM1, using Förster resonance energy transfer (FRET), a fluorescence spectroscopy technique sensitive to the distances between a fluorophore and a neighbouring acceptor.
• future: The authors observed only a small difference (17.2 . . .
  

   

  

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