Confrontation of alphafold models with experimental structures enlightens conformational dynamics supporting cyp102a1 functions

HIGHLIGHTS

  • who: Philippe Urban from the Toulouse Biotechnology Institute have published the Article: Confrontation of AlphaFold models with experimental structures enlightens conformational dynamics supporting CYP102A1 functions, in the Journal: Scientific Reports Scientific Reports
  • what: The present work illustrates that AF2A shares with the more finalized versions, noticeably AlphaFold-multimer, the capability to accurately model individual domains of modular proteins as well as the structure of potential intrachain or interchain complexes.
  • how: The set of the different modelling assays the authors carried out for this work is summarized in Fig 1a.

SUMMARY

     

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