Conjugation to a cell-penetrating peptide drives the tumour accumulation of the glp1r antagonist exendin(9-39)

HIGHLIGHTS

• who: Estel Collado Camps from the Department of Medical Imaging, Radboudumc, , HB Nijmegen, The Netherlands have published the research work: Conjugation to a cell-penetrating peptide drives the tumour accumulation of the GLP1R antagonist exendin(9-39), in the Journal: (JOURNAL)
• what: The authors demonstrate that penetratin robustly improves internalisation and tumour retention of exendin(9-39) opening new avenues for antagonist-based in vivo imaging of GLP1R. The authors compared exendin-4, exendin(9-39) and their respective C-terminal penetratin conjugates, exendin-4-Pen and exendin(9-39)-Pen, with regard to their . . .
  

   

  

  If you want to have access to all the content you need to log in!

  Thanks :)

  Username or Email

  Password

  Remember me

  Lost your password?

  If you don't have an account, you can create one here.