HIGHLIGHTS
- who: July et al. from the University of California, San Diego, United States have published the research: Connections between metabolism and epigenetics: mechanisms and novel anti-cancer strategy, in the Journal: (JOURNAL)
SUMMARY
In 1920s, Warburg firstly proposed (Kaye, 1998; Chinnaiyan et_al, 2012) that cancer cells display enhanced glycolysis and increased secretion of lactate even with abundant oxygen supply. Numerous excellent reviews have summarized the biology fundamentals of chromatin-modified proteins (CMPs) (Tessarz and Kouzarides, 2014; Piunti and Shilatifard, 2016; Soshnev et_al, 2016) and the therapeutic potentials to target CMPs in tumor (Pfister . . .
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