HIGHLIGHTS
- who: Gan Wu from the Department of Rheumatology, Yat-sen University, China have published the research: Connective tissue growth factor-targeting DNA aptamer suppresses pannus formation as diagnostics and therapeutics for rheumatoid arthritis, in the Journal: (JOURNAL)
- what: The CIA murine model was introduced to evaluate the function of AptW2-1-39-PEG in RA progression. The development of clinically effective therapeutic aptamers has lagged far behind that of therapeutic antibodies, which could be attributed to the following reasons: First, aptamers are oligonucleotides that are easily degraded by nucleases.
- how: The one-way . . .
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