Connexin 43 in mitochondria: what do we really know about its function?

HIGHLIGHTS

  • who: Paolo Bernardi and collaborators from the University of Padua, Italy have published the research work: Connexin 43 in Mitochondria: What Do We Really Know About Its Function?, in the Journal: (JOURNAL)
  • what: Taken together, this work shows that hemichannel opening and the ensuing electrical and Ca2+ consequences, had a significant impact on cardiomyocyte functioning.
  • future: Since the translocation of Cx43 to the inner mitochondrial membrane definitely involves more proteins/ protein complexes than the ones already described more research is needed to identify the exact pathways by which Cx43 or other connexins enter . . .

     

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