Consecutive injection of high-dose lipopolysaccharide modulates microglia polarization via trem2 to alter status of septic mice

HIGHLIGHTS

  • who: Zhiyun Qiu and collaborators from the Department of Anesthesiology, Zhongshan Hospital, Fudan University, Shanghai, China have published the paper: Consecutive Injection of High-Dose Lipopolysaccharide Modulates Microglia Polarization via TREM2 to Alter Status of Septic Mice, in the Journal: (JOURNAL) of 29/Dec/2022
  • what: The aim in this study was to investigate the interconnection between microglia polarization and in neuroinflammation. The authors reported that IFN-u03b2 regulated TREM2 expression and triggered the conversion of M2 (anti-inflammatory) phenotype-microglia to neuroinflammation. The study explored the role of TREM2 in sepsis caused by consecutive . . .

     

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