HIGHLIGHTS
- who: Ying-Jiun C. Chen from the (UNIVERSITY) have published the research: Conservation and diversity of the eukaryotic SAGA coactivator complex across kingdoms, in the Journal: (JOURNAL)
- what: Unlike other GCN5-containing complexes such as the metazoan-specific ATAC complex, SAGA is uniquely conserved in all eukaryotes.
SUMMARY
Paralogous ADA2A and ADA2B genes are encoded solely in higher eukaryotic genomes, and whether the GCN5-containing KAT module is incorporated into ATAC or SAGA is determined by its assembly with an either ADA2A or ADA2B protein. Of chromatin IP (ChIP) or affinity . . .
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