HIGHLIGHTS
- who: Tina Uroda from the Molecular Biology Laboratory (EMBL) Grenoble, des Martyrs, Grenoble, France University of have published the research work: Conserved Pseudoknots in lncRNA MEG3 Are Essential for Stimulation of the p53 Pathway, in the Journal: (JOURNAL)
- what: The authors report structural and functional studies of human maternally expressed gene 3 (MEG3) a tumor suppressor lncRNA that modulates the p53 response. To overcome the challenge posed for cellular probing by the complex alternative splicing pattern of MEG3, in the study the authors used WI38 fibroblasts to probe endogenous MEG3 (expression levels are reported in . . .
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