HIGHLIGHTS
- who: Maria A. Missinato from the (UNIVERSITY) have published the article: Conserved transcription factors promote cell fate stability and restrict reprogramming potential in differentiated cells, in the Journal: (JOURNAL)
- what: The authors report on the identification of four TFs (AJSZ) that promote cell fate stability and oppose cell fate reprogramming in both a lineageand cell type-independent manner. Given their conserved role as barriers to cell fate reprogramming, elevated expression in differentiated cells and reduced expression in fate-destabilized cancer and undifferentiated cells, the authors propose that AJSZ contribute to establish a Nature Communications | 14 . . .
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