Construction and evaluation of recombinant adenovirus candidate vaccines for chikungunya virus

HIGHLIGHTS

  • who: Liang Cao et al. from the College of Laboratory, Jilin Medical University, Jilin, China have published the Article: Construction and Evaluation of Recombinant Adenovirus Candidate Vaccines for Chikungunya Virus, in the Journal: Viruses 2022, 1779 of /2022/
  • what: We describe the development, identification, and immunization efficacy of recombinant adenovirus vaccines based on the envelope protein of E2/E1/E2-6K-E1 of CHIKV.
  • how: In this study an adenovirus 5-vector was used to construct recombinant adenovirus vaccines expressing E2 E1 or E2-6K-E1 of CHIKV. The significant difference at 14 . . .

     

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