HIGHLIGHTS
- who: Thomas Walther et al. from the # Present address: Institute of Natural Materials Technology, TU Dresden, Dresden, Germany have published the article: Construction of a synthetic metabolic pathway for the production of 2,4-dihydroxybutyric acid from homoserine, in the Journal: (JOURNAL) of 14/09/2017
- what: The work showed that several natural candidate transaminase and 2-hydroxyacid dehydrogenases had significant homoserine transaminase and OHB reductase activity, respectively. The authors intended to make use of this pronounced promiscuity of transaminases and characterized enzymes from three different classes of aminotransferases, namely the aspartate (EC-AspC), Version . . .
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