HIGHLIGHTS
- who: Albert Perez-Riba from the Department of Pharmacology, University of Cambridge, Cambridge, United Kingdom have published the research work: Context-Dependent Energetics of Loop Extensions in a Family of Tandem-Repeat Proteins, in the Journal: (JOURNAL)
- what: The authors explore the possibility of extending the loops between repeats to enable further diversification and the authors investigate how this modification affects stability and folding cooperativity. The study provides important and, to the knowledge , new insights into the TPR proteins, a family with over 500,000 sequences in which long inter-repeat loops are often observed . . .
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