Continued complexity of mutations in omicron sublineages

HIGHLIGHTS

• who: Austin N. Spratt and colleagues from the Bond Life Sciences Center, University of Missouri, Columbia, MO, USA have published the article: Continued Complexity of Mutations in Omicron Sublineages, in the Journal: Biomedicines 2022, 2593 of 12/06/2022
• what: The analyses presented above show that the Omicron sublineages have a complex mutation profile, including mutually exclusive (i.e., K417N and K417T) and revertant mutations (i.e., G446 and G496).
• how: For MD simulations the authors used the crystal_structure of the spike receptor-binding domain (S-RBD) in complex with human angiotensin-converting . . .
  

   

  

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