Continuous germinal center invasion contributes to the diversity of the immune response

HIGHLIGHTS

• who: Thomas Hu00e4gglu00f6f from the Laboratory Rockefeller University, New York, NY, USA have published the Article: Continuous germinal center invasion contributes to the diversity of the immune response, in the Journal: (JOURNAL)
• what: The experiments show that naive B cells continuously enter GCs where they compete for T cell help and undergo clonal expansion.
• how: In this reaction cycles of B cell division coupled to somatic mutation in the dark zone are followed by migration to the light zone where newly developed receptors are tested for binding to antigen displayed on follicular dendritic . . .
  

   

  

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