HIGHLIGHTS
- who: CITATION and colleagues from the University of Cambridge, United Kingdom have published the article: Contribution of integrin adhesion to cytokinetic abscission and genomic integrity, in the Journal: (JOURNAL)
- what: The current review discusses the role of integrin signals in the mitotic exit of mammalian cells, as well as the impact of their dysfunction in the context of centrosome activities and genomic integrity.
SUMMARY
Integrins do not have intrinsic enzyme activity but trigger several signaling pathways through ligand-induced clustering, which via the integrin-associated talin-kindlinpaxillin complex, brings focal adhesion . . .
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