Contribution of tissue transglutaminase to the severity of hepatic fibrosis resulting from schistosoma japonicum infection through the regulation of il-33/st2 expression

HIGHLIGHTS

  • who: Zhi-Yong Li from the (UNIVERSITY) have published the paper: Contribution of tissue transglutaminase to the severity of hepatic fibrosis resulting from Schistosoma japonicum infection through the regulation of IL-33/ST2 expression, in the Journal: (JOURNAL)
  • what: This study investigated the link between tTG and IL-33/ST2 in the induction of fibrogenesis during Sj infection in mice.
  • how: The IHC results showed that IL-33 was mostly expressed in the cells of the outer rim of the granulomas whereas ST2 was essentially expressed inside granulomas where macrophages are extensively present . . .

     

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