Control of polarized assembly of actin filaments in cell motility

HIGHLIGHTS

  • who: Marie-France Carlier from the Institut de Biologie Intégrative de la Cellule, CNRS, Gif-sur Yvette, France have published the research: Control of polarized assembly of actin filaments in cell motility, in the Journal: (JOURNAL)

SUMMARY

    Because the assembly-disassembly kinetics are faster at the barbed ends than at the pointed ends as compared to the rate of ATP hydrolysis, terminal actin subunits at barbed ends are mostly ATP or ADP-Pi bound, while ADP-actin is mainly exposed to the pointed end (Fig 1a, b). It can only amplify the . . .

     

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