Control of stereocilia length during development of hair bundles

HIGHLIGHTS

  • who: Jocelyn F. Krey and colleagues from the Oregon Hearing Research Center and Vollum Institute, Oregon Health and Science University, Portland have published the paper: Control of stereocilia length during development of hair bundles, in the Journal: (JOURNAL)
  • what: While CDH23-PCDH15 tip links gate transduction_channels and transduction impacts bundle development , the authors show here that CDH23 and PCDH15 are also essential for coordinating the lengths of adjacent stereocilia in the same row. In IHCs, the authors propose that dimeric complexes of CDH23 and PCDH15 carry out the same function throughout development.
  • how . . .

     

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