HIGHLIGHTS
- who: Jan Zrimec from the (UNIVERSITY) have published the paper: Controlling gene expression with deep generative design of regulatory DNA, in the Journal: (JOURNAL) of 27/01/2022
- what: Driven by these findings, the authors aimed to improve upon current mutagenesis capabilities15,30,45 with a more controlled approach for mapping sequence-function landscapes and designing synthetic regulatory DNA. The authors explored whether de novo functional regulatory DNA, spanning the whole gene regulatory structure and producing desired gene_expression levels, can be generated just from the knowledge of natural regulatory_sequences. To calculate the relevance of the . . .
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