Convergence of external crohn’s disease risk factors on intestinal bacteria

HIGHLIGHTS

  • who: Brian K. Coombes from the Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, ON, Canada, Michael GDeGroote have published the research: Convergence of external Crohn’s disease risk factors on intestinal bacteria, in the Journal: (JOURNAL)
  • what: Using this model, it was shown that AIEC is resistant to innate antimicrobial defenses at the epithelial surface, including resistance to antimicrobial peptides released by Paneth cells and colonocytes .
  • future: Research is needed to determine how levels of F. prausnitzii might dictate the fine balance between health and disease in the gut. As of . . .

     

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