Convergent evolution of a parasite-encoded complement control protein-scaffold to mimic binding of mammalian tgf-β to its receptors, tβri and tβrii

HIGHLIGHTS

• who: Ananya Mukundan from the Ananya Mukundan1, Chang-Hyeock Byeon1, Cynthia SHinck1, Kyle Cunningham2, Tiffany Campion2, Danielle J. Smyth2, Rick M. Maizels2, and Andrew P. Hinck1, * From the Department of Structural Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania USA have published the research: Convergent evolution of a parasite-encoded complement control protein-scaffold to mimic binding of mammalian TGF-u03b2 to its receptors, Tu03b2RI and Tu03b2RII, in the Journal: (JOURNAL) of December/11,/2021
• what: The authors demonstrate that binding is modular, with D1-D2 binding to Tu03b2RI and D3 binding to Tu03b2RII . . .
  

   

  

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