Cooperative interaction of ews with creb-binding protein selectively activates hepatocyte nuclear factor 4-mediated transcription*

HIGHLIGHTS

  • who: Natsumi Araya from the (UNIVERSITY) have published the research work: Cooperative Interaction of EWS with CREB-binding Protein Selectively Activates Hepatocyte Nuclear Factor 4-mediated Transcription*, in the Journal: (JOURNAL) of November/22,/2002
  • how: To test for transcriptional co-activations by EWS on the endogenous promoter sequences the authors carried out transfection experiments using lucif- EWS as a Co-activator for HNF4 erase reporter plasmids containing each HNF4-targeted gene promoter.

SUMMARY

    Although EWS is predicted to be an RNA-binding protein, an inherent EWS nuclear function has not . . .

     

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