HIGHLIGHTS
- who: Nitu Saha from the (UNIVERSITY) have published the article: Copper inhibits protein maturation in the secretory pathway by targeting the Sec61 translocon in Saccharomyces cerevisiae, in the Journal: (JOURNAL) of January/20,/2022
- what: Using immunoblotting, microscopy, and spot test assays, the authors show that excess copper inhibits the Sec61 translocon function and causes accumulation of two well-known posttranslationally translocated proteins, Gas1 (glycophospholipidanchored surface protein) and CPY (carboxypeptidase Y), in the cytosol. In this communication, the authors attempt to address the question by checking the effect of copper on two different secretory proteins . . .
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